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Table 1 Characteristics of included patients by receipt of ultrasound enhancing agents in claims versus electronic medical records

From: Validation of administrative claims to identify ultrasound enhancing agent use

Baseline characteristics of individuals with UEAs identified in claims and EMR data

Patient characteristic

Number (%) with UEA in Claims (N = 10,461)

Number (%) with UEA with in EMR (N = 12,853)

p-value

Age group (y)

0.02

 0–17

0 (0.0%)

4 (0.0%)

 18–34

226 (2.2%)

334 (2.6%)

 35–44

515 (4.9%)

669 (5.2%)

 45–54

1181 (11.3%)

1528 (11.9%)

 55–64

2479 (23.7%)

3085 (24.0%)

 ≥ 65

6060 (57.9%)

7233 (56.3%)

Sex

< 0.001

 Female

4720 (45.1%)

5836 (45.4%)

 Male

5741 (54.9%)

6979 (54.3%)

 Unknown

0 (0.0%)

38 (0.3%)

Any malignancy

1676 (16.0%)

2019 (15.7%)

0.53

Metastatic malignancy

464 (4.4%)

547 (4.3%)

0.52

Cerebrovascular disease

1698 (16.2%)

1990 (15.5%)

0.12

Chronic pulmonary disease

3169 (30.3%)

3726 (29.0%)

0.03

Congestive heart failure

3476 (33.2%)

4150 (32.3%)

0.13

Connective tissue Diseases

406 (3.9%)

481 (3.7%)

0.61

Dementia

242 (2.3%)

309 (2.4%)

0.68

Diabetes

 With complications

2054 (19.6%)

2447 (19.0%)

0.26

 Without complications

3778 (36.1%)

4393 (34.2%)

0.002

HIV/Aids

78 (0.7%)

112 (0.9%)

0.32

Liver disease

 Mild

1214 (11.6%)

1490 (11.6%)

0.99

 Moderate or severe

128 (1.2%)

183 (1.4%)

0.21

Myocardial infarction

1565 (15.0%)

1940 (15.1%)

0.79

Paraplegia/hemiplegia

167 (1.6%)

232 (1.8%)

0.24

Peptic ulcer disease

207 (2.0%)

245 (1.9%)

0.73

Peripheral arterial disease

2368 (22.6%)

2825 (22.0%)

0.24

Renal disease

1872 (17.9%)

2253 (17.5%)

0.48

COVID-19

526 (5.0%)

671 (5.2%)

0.53

  1. AIDS acquired immune deficiency syndrome, COVID-19 coronavirus disease 2019, EMR electronic medical record, HIV human immunodeficiency virus, N number of individuals, UEA ultrasound enhancing agents, y year. p-values significant at a p < 0.05 level are bolded
  2. Shown are the characteristics of included patients by whether they were identified as having received ultrasound enhancing agents (UEAs) through billing claims or electronic medical record (EMR) data within a 1-day window. P-values for Pearson’s chi-squared tests to evaluate pairwise difference across groups are shown