Table 3 Abnormalities found during screening and subsequent cardiac MRI in the 10 individuals diagnosed with DCM.
From: Implementing a clinical scientist-led screening clinic for hypertrophic and dilated cardiomyopathies
Proband Diagnosis | Age | Gender | Ethnicity | ECG abnormality | Echo Abnormality | Cardiac MRI |
|---|---|---|---|---|---|---|
DCM | 35 | M | White | Complete heart block | Dilated LV cavity, LVEF 53% | Increased indexed LV end-diastolic volume with mildly reduced systolic function (LVEF 53%). Basal septal mid-wall linear and RV inferior insertion point fibrosis |
DCM | 23 | M | White | Nil | LVEF 48%, GLS − 14.3% | Normal indexed LV end-diastolic volume with mildly reduced systolic function (LVEF 53%); elongated anterior mitral leaflet with papillary muscle variants and single myocardial crypt |
DCM | 41 | M | White | Voltage criteria for LVH | Borderline LV cavity dimensions Low-normal LVEF 53% | Increased indexed LV end-diastolic volume with mildly reduced systolic function (LVEF 54%) |
DCM | 32 | M | White | Nil | Dilated LV volumes | Increased indexed LV end-diastolic volume with mildly impaired systolic function (LVEF 50%). Normal RV size and function. |
DCM | 37 | M | Afro-Caribbean | Nil | LVEF 52%, GLS − 15% | Normal indexed LV end-diastolic volume with moderately impaired LV systolic function (LVEF 43%). Normal indexed RV volume with mild RV impairment (EF 40%). |
DCM | 26 | F | White | Nil | LVEF 47% | Normal Indexed LV end-diastolic volume with moderately impaired global systolic function (LVEF 43%) |
DCM | 55 | M | White | Nil | LVEF 42%, GLS − 15% | Normal Indexed LV end-diastolic volume with mildly impaired global systolic function (LVEF 50%). Basal-to-mid mid-wall septal fibrosis; epicardial and mid-wall fibrosis of the basal-to-mid lateral and inferior walls |
DCM | 27 | M | White | Nil | Dilated LV volumes with borderline EF (53%) | Normal indexed LV end-diastolic volume with moderately impaired global systolic function (LVEF 43%) |
DCM | 30 | F | White | T-wave inversion V1-V6 | LVEF 50% | Normal LV with borderline reduced systolic function (LVEF 55%) and increased trabeculation of the LV anterior wall |
DCM | 46 | M | White | Atrial ectopy | LVEF 50%, GLS − 16% | Unable to tolerate full cardiac MRI scan due to claustrophobia |