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Diagnosis and management of hypertrophic cardiomyopathy

Abstract

The clinical spectrum of hypertrophic cardiomyopathy (HCM) is complex and includes a variety of phenotypes, which leads to different types of manifestations. Although most of the patients are asymptomatic, a significant proportion of them will develop symptoms or risk of arrhythmias and sudden cardiac death (SCD). Therefore, the objectives of HCM diagnosis and management are to relieve the patients’ symptoms (chest pain, heart failure, syncope, palpitations, etc.), prevent disease progression and major cardiovascular complications and SCD. The heterogeneity of HCM patterns, their symptoms and assessment is a challenge for the cardiologist.

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Funding

A S Vischer was supported by a research grant from the Swiss Heart Rhythm foundation. M C Perez-Tome was supported by a research grant from the Spanish Society of Cardiology. S Castelletti was supported by a research grant from the European Society of Cardiology.

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Correspondence to Antonis Pantazis MD.

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Pantazis, A., Vischer, A.S., Perez-Tome, M.C. et al. Diagnosis and management of hypertrophic cardiomyopathy. Echo Res Pract 2, R45–R53 (2015). https://doi.org/10.1530/ERP-15-0007

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Key Words

  • hypertrophic cardiomyopathy
  • left ventricular outflow tract obstruction
  • amyloidosis
  • cardiac magnetic resonance imaging
  • Anderson-Fabry’s disease
  • Friedreich’s ataxia