- Review
- Open access
- Published:
Stress echocardiography in patients with morbid obesity
Echo Research & Practice volume 3, page R18 (2016)
Abstract
The incidence of significant obesity is rising across the globe. These patients often have a clustering of cardiovascular risk factors and are frequently referred for noninvasive cardiac imaging tests. Stress echocardiography (SE) is widely used for assessment of patients with known or suspected coronary artery disease (CAD), but its clinical utility in morbidly obese patients (in whom image quality may suffer due to body habitus) has been largely unknown. The recently published Stress Ultrasonography in Morbid Obesity (SUMO) study has shown that SE, when performed appropriately with ultrasound contrast agents (whether performed with physiological or pharmacological stress), has excellent feasibility and appropriately risk stratifies morbidly obese patients, including identification of patients who require revascularization. This article reviews the evidence supporting the use of echocardiographic techniques in morbidly obese patients for assessment of known or suspected CAD and briefly discusses other noninvasive modalities, including magnetic resonance and nuclear techniques, comparing and contrasting these techniques against SE.
References
World Health Organization (WHO) 2013 Obesity and overweight. Access date 15 January 2014. Geneva, Switzerland: WHO. (available at: http://www.who.int/mediacentre/factsheets/fs311/en/
Sturm R 2007 Increases in morbid obesity in the USA: 2000–2005. Public Health 121 492–496. (doi:10.1016/j.puhe.2007.01.006)
Grundy SM, Barondess JA, Bellegie NJ, Fromm H, Greenway F, Halsted CH, Huth EJ, Kumanyika SK, Reisin E, Robinson MK, et al. 1991 Gastrointestinal surgery for severe obesity. Annals of Internal Medicine 115 956–961. (doi:10.7326/0003-4819-115-12-956)
Uppot RN 2007 Impact of obesity on radiology. Radiologic Clinics of North America 45 231–246. (doi:10.1016/j.rcl.2007.03.001)
Plana JC, Mikati IA, Dokainish H, Lakkis N, Abukhalil J, Davis R, Hetzell BC & Zoghbi WA 2008 A randomized cross-over study for evaluation of the effect of image optimization with contrast on the diagnostic accuracy of dobutamine echocardiography in coronary artery disease the OPTIMIZE trial. JACC: Cardiovascular Imaging 1 145–152. (doi:10.1016/j.jcmg.2007.10.014)
Shah BN, Balaji G, Alhajiri A, Ramzy IS, Ahmadvazir S & Senior R 2013 Incremental diagnostic and prognostic value of contemporary stress echocardiography in a chest pain unit: mortality and morbidity outcomes from a real-world setting. Circulation: Cardiovascular Imaging 6 202–209. (doi:10.1161/CIRCIMAGING.112.980797)
Sicari R, Nihoyannopoulos P, Evangelista A, Kasprzak J, Lancellotti P, Poldermans D, Voigt JU & Zamorano JL 2008 Stress echocardiography expert consensus statement: European association of echocardiography. European Journal of Echocardiography 9 415–437. (doi:10.1093/ejechocard/jen175)
Pellikka PA, Nagueh SF, Elhendy AA, Kuehl CA & Sawada SG 2007 American Society of Echocardiography recommendations for performance, interpretation, and application of stress echocardiography. Journal of the American Society of Echocardiography 20 1021–1041. (doi:10.1016/j.echo.2007.07.003)
Shah BN, Zacharias K, Pabla JS, Karogiannis N, Calicchio F, Balaji G, Alhajiri A, Ramzy IS, Elghamaz A, Gurunathan S, et al. 2016 The clinical impact of contemporary stress echocardiography in morbid obesity for the assessment of coronary artery disease. Heart 102 370–375. (doi:10.1136/heartjnl-2015-308796)
Murphy M, Krothapalli S, Cuellar J, Kanjanauthai S, Heeke B, Gomadam PS, Guha A, Barnes VA, Litwin SE & Sharma GK 2014 Prognostic value of normal stress echocardiography in obese patients. Journal of Obesity 2014 419724. (doi:10.1155/2014/419724)
Silveira MG, Sousa AC, Santos MA, Tavares Ida S, Andrade SM, Melo LD, Andrade LS, Santos EL & Oliveira JL 2015 Assessment of myocardial ischemia in obese individuals undergoing physical stress echocardiography. Arquivos Brasileiros de Cardiologia 104 394–400. (doi:10.5935/abc.20150006)
Lerakis S, Kalogeropoulos AP, El-Chami MF, Georgiopoulou VV, Abraham A, Lynch SA, Lewis AJ, Leach GC, Osier EJ, Veledar E, et al. 2007 Transthoracic dobutamine stress echocardiography in patients undergoing bariatric surgery. Obesity Surgery 17 1475–1481.
Supariwala A, Makani H, Kahan J, Pierce M, Bajwa F, Dukkipati SS, Teixeira J & Chaudhry FA 2014 Feasibility and prognostic value of stress echocardiography in obese, morbidly obese, and super obese patients referred for bariatric surgery. Echocardiography 31 879–885. (doi:10.1111/echo.12481)
Bhat G, Daley K, Dugan M & Larson G 2004 Preoperative evaluation for bariatric surgery using transesophageal dobutamine stress echocardiography. Obesity Surgery 14 948–951. (doi:10.1381/0960892041719554)
Garimella S, Longaker RA & Stoddard MF 2002 Safety of transesophageal echocardiography in patients who are obese. Journal of the American Society of Echocardiography 15 1396–1400.
Madu EC 2000 Transesophageal dobutamine stress echocardiography in the evaluation of myocardial ischemia in morbidly obese subjects. Chest 117 657–661. (doi:10.1378/chest.117.3.657)
Legault S, Senechal M, Bergeron S, Arsenault M, Tessier M, Guimond J & Poirier P 2010 Usefulness of an accelerated transoesophageal stress echocardiography in the preoperative evaluation of high risk severely obese subjects awaiting bariatric surgery. Cardiovascular Ultrasound 8 30. (doi:10.1186/1476-7120-8-30)
Hansen CL, Woodhouse S & Kramer M 2000 Effect of patient obesity on the accuracy of thallium-201 myocardial perfusion imaging. American Journal of Cardiology 85 749–752. (doi:10.1016/S0002-9149(99)00853-X)
DeCicco AE, Sokil AB, Marhefka GD, Reist K & Hansen CL 2015 Feasibility of spect myocardial perfusion imaging in the super-obese using a multi-head semiconductor camera with attenuation correction. Journal of Nuclear Cardiology 22 344–350. (doi:10.1007/s12350-014-0018-y)
Duvall WL, Croft LB, Corriel JS, Einstein AJ, Fisher JE, Haynes PS, Rose RK & Henzlova MJ 2006 Spect myocardial perfusion imaging in morbidly obese patients: image quality, hemodynamic response to pharmacologic stress, and diagnostic and prognostic value. Journal of Nuclear Cardiology 13 202–209. (doi:10.1007/BF02971244)
Chow BJ, Dorbala S, Di Carli MF, Merhige ME, Williams BA, Veledar E, Min JK, Pencina MJ, Yam Y, Chen L, et al. 2014 Prognostic value of pet myocardial perfusion imaging in obese patients. JACC: Cardiovascular Imaging 7 278–287. (doi:10.1016/j.jcmg.2013.12.008)
Shah RV, Heydari B, Coelho-Filho O, Abbasi SA, Feng JH, Neilan TG, Francis S, Blankstein R, Steigner M, Jerosch-Herold M & Kwong RY 2014 Vasodilator stress perfusion CMR imaging is feasible and prognostic in obese patients. JACC: Cardiovascular Imaging 7 462–472. (doi:10.1016/j.jcmg.2013.11.011)
Khawaja OA, Shaikh KA & Al-Mallah MH 2010 Meta-analysis of adverse cardiovascular events associated with echocardiographic contrast agents. American Journal of Cardiology 106 742–747.
Wei K, Mulvagh SL, Carson L, Davidoff R, Gabriel R, Grimm RA, Wilson S, Fane L, Herzog CA, Zoghbi WA, et al. 2008 The safety of definity and optison for ultrasound image enhancement: a retrospective analysis of 78,383 administered contrast doses. Journal of the American Society of Echocardiography 21 1202–1206. (doi:10.1016/j.echo.2008.07.019)
Main ML, Ryan AC, Davis TE, Albano MP, Kusnetzky LL & Hibberd M 2008 Acute mortality in hospitalized patients undergoing echocardiography with and without an ultrasound contrast agent (multicenter registry results in 4,300,966 consecutive patients). American Journal of Cardiology 102 1742–1746. (doi:10.1016/j.amjcard.2008.08.019)
Funding
This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.
About this article
Cite this article
Shah, B.N., Senior, R. Stress echocardiography in patients with morbid obesity. Echo Res Pract 3, R18 (2016). https://doi.org/10.1530/ERP-16-0010
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1530/ERP-16-0010