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Analysis of chronic aortic regurgitation by 2D and 3D echocardiography and cardiac MRI

Echo Research & Practice volume 5, pages 51–62 (2018)Cite this article

Abstract

Purpose: The study compares the feasibility of the quantitative volumetric and semi-quantitative approach for quantification of chronic aortic regurgitation (AR) using different imaging modalities.

Methods: Left ventricular (LV) volumes, regurgitant volumes (RVol) and regurgitant fractions (RF) were assessed retrospectively by 2D, 3D echocardiography and cMRI in 55 chronic AR patients. Semi-quantitative parameters were assessed by 2D echocardiography.

Results: 22 (40%) patients had mild, 25 (46%) moderate and 8 (14%) severe AR. The quantitative volumetric approach was feasible using 2D, 3D echocardiography and cMRI, whereas the feasibility of semi-quantitative parameters varied considerably. LV volume (LVEDV, LVESV, SVtot) analyses showed good correlations between the different imaging modalities, although significantly increased LV volumes were assessed by cMRI. RVol was significantly different between 2D/3D echocardiography and 2D echocardiography/cMRI but was not significantly different between 3D echocardiography/cMRI. RF was not statistically different between 2D echocardiography/cMRI and 3D echocardiography/cMRI showing poor correlations (r < 0.5) between the different imaging modalities. For AR grading by RF, moderate agreement was observed between 2D/3D echocardiography and 2D echocardiography/cMRI and good agreement was observed between 3D echocardiography/cMRI.

Conclusion: Semi-quantitative parameters are difficult to determine by 2D echocardiography in clinical routine. The quantitative volumetric RF assessment seems to be feasible and can be discussed as an alternative approach in chronic AR. However, RVol and RF did not correlate well between the different imaging modalities. The best agreement for grading of AR severity by RF was observed between 3D echocardiography and cMRI. LV volumes can be verified by different approaches and different imaging modalities.

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Funding

This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.

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Authors and Affiliations

  1. Department of Cardiology, Leipzig University Hospital, Leipzig, Germany

    Stephan Stoebe, Michael Metze MD, Daniel Jurisch MD, Ulrich Laufs PhD, Dietrich Pfeiffer PhD & Andreas Hagendorff PhD

  2. Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark

    Bhupendar Tayal MD

  3. Department of Diagnostic and Interventional Radiology, Leipzig University Hospital, Leipzig, Germany

    Kilian Solty BoA

  4. Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany

    Kilian Solty BoA

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  1. Stephan Stoebe
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  2. Michael Metze MD
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Correspondence to Stephan Stoebe.

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Stoebe, S., Metze, M., Jurisch, D. et al. Analysis of chronic aortic regurgitation by 2D and 3D echocardiography and cardiac MRI. Echo Res Pract 5, 51–62 (2018). https://doi.org/10.1530/ERP-17-0083

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Echo Research & Practice

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