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The current role of echocardiography in acute aortic syndrome

Abstract

Acute aortic syndrome (AAS) comprises a range of interrelated conditions caused by disruption of the medial layer of the aortic wall, including aortic dissection, intramural haematoma and penetrating aortic ulcer. Since mortality from AAS is high, a prompt and accurate diagnosis using imaging techniques is paramount. Both transthoracic (TTE) and transoesophageal echocardiography (TEE) are useful in the diagnosis of AAS. TTE should be the first imaging technique to evaluate patients with thoracic pain in the emergency room. Should AAS be suspected, contrast administration is recommended when images are not definitive. TEE allows high-quality images in thoracic aorta. The main drawback of this technique is that it is semi-invasive and the presence of a blind area that limits visualisation of the distal ascending aorta near. TEE identifies the location and size of the entry tear, secondary communications, true lumen compression and the dynamic flow pattern of false lumen. Although computed tomography (CT) is the most used imaging technique in the diagnosis of AAS, echocardiography offers complementary information relevant for its management. The best imaging strategy for appropriately diagnosing and assessing AAS is to combine CT, mainly ECG-gated contrast-enhanced CT, and TTE. Currently, TEE tends to be carried out in the operating theatre immediately before surgical or endovascular therapy and in monitoring their results. The aims of this review are to establish the current role of echocardiography in the diagnosis and management of AAS based on its advantages and limitations.

References

  1. Nienaber CA, Clough RE, Sakalihasan N, Suzuki T, Gibbs R, Mussa F, Jenkins MP, Thompson MM, Evangelista A, Yeh JS, et al. Aortic dissection. Nature Reviews: Disease Primers 2016 2 16071. (https://doi.org/10.1038/nrdp.2016.71)

    PubMed  Google Scholar 

  2. Landenhed M, Engström G, Gottsäter A, Caulfield MP, Hedblad B, Newton‐Cheh C, Melander O & Smith JG. Risk profiles for aortic dissection and ruptured or surgically treated aneurysms: a prospective cohort study. Journal of the American Heart Association 2015 4 e001513. (https://doi.org/10.1161/JAHA.114.001513)

    Article  Google Scholar 

  3. Tsai TT, Nienaber CA & Eagle KA. Acute aortic syndromes. Circulation 2005 112 3802–3813. (https://doi.org/10.1161/CIRCULATIONAHA.105.534198)

    Article  Google Scholar 

  4. Evangelista Masip A. Progress in the acute aortic syndrome. Revista Española de Cardiología 2007 60 428–439. (https://doi.org/10.1157/13101646)

    Article  Google Scholar 

  5. Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, Evangelista A, Falk V, Frank H, Gaemperli O, et al. ESC guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC). European Heart Journal 2014 35 2873–2926. (https://doi.org/10.1093/eurheartj/ehu281)

    Article  Google Scholar 

  6. Goldstein SA, Evangelista A, Abbara S, Arai A, Asch FM, Badano LP, Bolen MA, Connolly HM, Cuéllar-Calàbria H, Czerny M, et al. Multimodality imaging of diseases of the thoracic aorta in adults: from the american society of echocardiography and the European association of cardiovascular imaging: endorsed by the society of cardiovascular computed tomography and society for cardiovascular magnetic resonance. Journal of the American Society of Echocardiography 2015 28 119–182. (https://doi.org/10.1016/j.echo.2014.11.015)

    Article  Google Scholar 

  7. Evangelista A, Carro A, Moral S, Teixidó-Turà G, Rodríguez-Palomares JF, Cuéllar H, García-Dorado D. Imaging modalities for the early diagnosis of acute aortic síndrome. Nature Reviews: Cardiology 2013 10 477–486. (https://doi.org/10.1038/nrcardio.2013.92)

    PubMed  Google Scholar 

  8. Bhave NM, Nienaber CA, Clough RE & Eagle KA. Multimodality imaging of thoracic aortic diseases in adults. JACC: Cardiovascular Imaging 2018 11 902–919. (https://doi.org/10.1016/j.jcmg.2018.03.009)

    PubMed  Google Scholar 

  9. Evangelista A, Rabasa JM, Mosquera VX, Barros A, Fernández-Tarrio R, Calvo-Iglesias F, Ferrera C, Rozado J, López-Ayerbe J, Garrote C, et al. Diagnosis, management and mortality in acute aortic syndrome: results of the Spanish Registry of Acute Aortic Syndrome (RESA-II). European Heart Journal: Acute Cardiovascular Care 2016 7 602–608. (https://doi.org/10.1177/2048872616682343)

    PubMed  Google Scholar 

  10. Evangelista A, Flachskampf FA, Erbel R, Antonini-Canterin F, Vlachopoulos C, Rocchi G, Sicari R, Nihoyannoupoulos P & Zamorano J, European Association of Echocardiography, et al. Echocardiography in aortic diseases: EAE recommendations for clinical practice. European Journal of Echocardiography 2010 11 645–658. (https://doi.org/10.1093/ejechocard/jeq056)

    Article  Google Scholar 

  11. Granato JE, Dee P & Gibson RS. Utility of echocardiography in suspected ascending aortic dissection. American Journal of Cardiology 1985 56 123–129. (https://doi.org/10.1016/0002-9149(85)90579-X)

    Article  CAS  Google Scholar 

  12. Erbel R, Engberding R, Daniel W, Roetlandt J, Visser C & Rennollet H. Echocardiography in diagnosis of aortic dissection. Lancet 1989 1 457–461. (https://doi.org/10.1016/S0140-6736(89)91364-0)

    Article  CAS  Google Scholar 

  13. Evangelista A, Avegliano G, Aguilar R, Cuellar H, Igual A, González-Alujas T, Rodriguez-Palomares J, Mahia P, Garcia-Dorado D. Impact of contrast-enhanced echocardiography on the diagnostic algorithm of acute aortic dissection. European Heart Journal 2010 31 472–479. (https://doi.org/10.1093/eurheartj/ehp505)

    Article  Google Scholar 

  14. Shiga T, Wajima Z, Apfel CC, Inoue T & Ohe Y. Diagnostic accuracy of transesophageal echocardiography, helical computed tomography and magnetic resonance imaging for suspected thoracic aortic dissection. Systematic review and meta-analisis. Archives of Internal Medicine 2006 166 1350–1356. (https://doi.org/10.1001/archinte.166.13.1350)

    Article  Google Scholar 

  15. Flachskampf FA, Wouters PF, Edvardsen T, Evangelista A, Habib G, Hoffman P, Hoffman R, Lancellotti P, Pepi M & Donal E. Recommendations for transoesophageal echocardiography: EACVI update 2014. European Heart Journal: Cardiovascular Imaging 2014 15 353–365. (https://doi.org/10.1093/ehjci/jeu015)

    PubMed  Google Scholar 

  16. Meredith EL & Masani ND. Echocardiography in the emergency assessment of acute aortic syndromes. European Journal of Echocardiography 2009 10 i31–i39. (https://doi.org/10.1093/ejechocard/jen251)

    Article  Google Scholar 

  17. Pepi M, Campodonico J, Galli C, Tamborini G, Barbier P, Doria E, Maltagliati A, Alimento M & Spirito R. Rapid diagnosis and management of thoracic aortic dissection and intramural haematoma: a prospective study of advantages of multiplane vs biplane transoesophageal echocardiography. European Journal of Echocardiography 2000 1 72–79. (https://doi.org/10.1053/euje.2000.0002)

    Article  CAS  Google Scholar 

  18. Evangelista A, Garcia del Castillo H, González-Alujas MT, Domínguez Oronoz R, Salas A, Soler-Soler J. Diagnosis of ascending aorta dissection by transesophageal echocardiography. Utility of M-mode in the detection of artifacts. Journal of the American College of Cardiology 1996 27 102–107. (https://doi.org/10.1016/0735-1097(95)00414-9)

    Article  CAS  Google Scholar 

  19. Erbel R, Oelert H, Meyer J, Puth M, Mohr-Katoly S, Hausmann D, Daniel W, Maffei S, Caruso A, Covino FE, et al. Effect of medical and surgical therapy on aortic dissection evaluated by transesophageal echocardiography. Implications for prognosis and therapy. The European Cooperative Study Group on Echocardiography. Circulation 1993 87 1604–1615. (https://doi.org/10.1161/01.CIR.87.5.1604)

    Article  CAS  Google Scholar 

  20. Vilacosta I, San Roman JA, Aragoncillo P, Ferriere’s J, Mendez R, Graupner C, Battle E, Serrano J, Pinto A & Oyonarte JM. Penetrating atherosclerotic aortic ulcer: documentation by transesophageal echocardiography. Journal of the American College of Cardiology 1998 32 83–89. (https://doi.org/10.1016/S0735-1097(98)00194-6)

    Article  CAS  Google Scholar 

  21. Evangelista A, Salas A, Ribera A, Ferreira-González I, Cuellar H, Pineda V, González-Alujas T, Bijnens B, Permanyer-Miralda G, García-Dorado D. Long-term outcome of aortic dissection with patent false lumen. Circulation 2012 125 3133–3141. (https://doi.org/10.1161/CIRCULATIONAHA.111.090266)

    Article  Google Scholar 

  22. Evangelista A, Aguilar R, Cuellar H, Thomas M, Laynez A, Rodríguez-Palomares J, Mahía P, Gonzàlez-Alujas T, García-Dorado D. Usefulness of real-time three-dimensional transoesophageal echocardiography in the assessment of chronic aortic dissection. European Journal of Echocardiography 2011 12 272–277. (https://doi.org/10.1093/ejechocard/jeq191)

    Article  Google Scholar 

  23. Mukherjee D, Evangelista A, Nienaber CA, Sechtem U, Suzuki T, Trimarchi S, Llovet A, Myrmel T, O’Gara PT, Fang J, et al. Implications of periaortic hematoma in patients with acute aortic dissection (from the International Registry of Acute Aortic Dissection). American Journal of Cardiology 2005 96 1734–1738. (https://doi.org/10.1016/j.amjcard.2005.07.098)

    Article  Google Scholar 

  24. Movsowitz HD, Levine RA, Hilgenberg AD & Isselbacher EM. Transesophageal echocardiographic description of the mechanisms of aortic regurgitation in acute type A aortic dissection: implications for aortic valve repair. Journal of the American College of Cardiology 2000 36 884–890. (https://doi.org/10.1016/S0735-1097(00)00766-X)

    Article  CAS  Google Scholar 

  25. Orihashi K, Matsuura Y, Sueda T, Watari M, Okada K, Sugawara Y & Ishii O. Aortic arch branches are no longer a blind zone for transesophageal echocardiography: a new eye for aortic surgeons. Journal of Thoracic and Cardiovascular Surgery 2000 120 466–472. (https://doi.org/10.1067/mtc.2000.108289)

    Article  CAS  Google Scholar 

  26. David TE & Feindel CM. An aortic valve-sparing operation for patients with aortic incompetence and aneurysm of the ascending aorta. Journal of Thoracic and Cardiovascular Surgery 1992 103 617–621.

    Article  CAS  Google Scholar 

  27. Ehrlich MP, Ergin MA, McCullough JN, Lansman SL, Galla JD, Bodian CA, Apaydin A & Griepp RB. Results of immediate surgical treatment of all acute type A dissections. Circulation 2000 102 (Supplement III) 248–252. (https://doi.org/10.1161/01.CIR.102.suppl_3.III-248)

    Google Scholar 

  28. Cao P, De Rango P, Czerny M, Evangelista A, Fattori R, Nienaber C, Rousseau H & Schepens M. Systematic review of clinical outcomes in hybrid procedures for aortic arch dissections and other arch diseases. Journal of Thoracic and Cardiovascular Surgery 2012 144 1286–1300.e2. (https://doi.org/10.1016/j.jtcvs.2012.06.013)

    Article  Google Scholar 

  29. Jonker FHW, Patel HJ, Upchurch GR, Williams DM, Montgomery DG, Gleason TG, Braverman AC, Sechtem U, Fattori R, Di Eusanio M, et al. Acute type B aortic dissection complicated by visceral ischemia. Journal of Thoracic and Cardiovascular Surgery 2015 149 1081.e1–1086.e1. (https://doi.org/10.1016/j.jtcvs.2014.11.012)

    Article  Google Scholar 

  30. Nienaber CA, Kische S, Rousseau H, Eggebrecht H, Rehders TC, Kundt G, Glass A, Scheinert D, Czerny M, Kleinfeldt T, et al. Endovascular repair of Type B aortic dissection. Long-term results of the randomized investigation of stent grafts in Aortic Dissection Trial. Circulation: Cardiovascular Interventions 2013 6 407–416. (https://doi.org/10.1161/CIRCINTERVENTIONS.113.000463)

    CAS  Google Scholar 

  31. Tsai TT, Evangelista A, Nienaber CA, Myrmel T, Meinhardt G, Cooper JV, Smith DE, Suzuki T, Fattori R, Llovet A, et al. Partial thrombosis of the false lumen in patients with acute Type B aortic dissection. New England Journal of Medicine 2007 357 349–359. (https://doi.org/10.1056/NEJMoa063232)

    Article  CAS  Google Scholar 

  32. Evangelista A, Dominguez R, Sebastia C, Salas A, Permanyer-Miralda G, Avegliano G, Elorz C, González-Alujas T, García Del Castillo H, Soler-Soler J. Long-term follow-up of aortic intramural hematoma. Circulation 2003 108 583–589. (https://doi.org/10.1161/01.CIR.0000081776.49923.5A)

    Article  Google Scholar 

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Correspondence to Arturo Evangelista MD PhD FESC.

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Evangelista, A., Maldonado, G., Gruosso, D. et al. The current role of echocardiography in acute aortic syndrome. Echo Res Pract 6, R53–R63 (2019). https://doi.org/10.1530/ERP-18-0058

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