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How to run a specialist valve clinic: the history, examination and exercise test

Abstract

Echocardiography is the key to the detection and initial assessment of valve disease. The examination helps differentiate severe from moderate disease if this is unclear from the echocardiogram, but is less useful than echocardiography for surveillance. However, the history is extremely important because symptoms are an indication for surgery in all types of valve disease. In aortic stenosis, the mortality rises soon after the onset of exertional breathlessness or chest tightness. Exercise testing is an extension of the history and may reveal symptoms in apparently asymptomatic patients. This article discusses the history, examination and exercise testing in patients either newly referred or under routine follow-up in a specialist valve clinic.

References

  1. Baumgartner H, Falk V, Bax JJ, De Bonis M, Hamm C, Holm PH, Iung B, Lancellotti P, Lansac E, Muñoz DRB, et al. 2017 ESC/EACTS guidelines for the management of valvular heart disease. European Heart Journal 201738. https://doi.org/10.1093/eurheartj/ehx391)

  2. Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP, Guyton RA, O'Gara P, Ruiz CE, Skubas NJ, Sorajje P, et al. 2014 AHA/ACC Guideline for the management of patients with valvular heart disease. Circulation 2014129. https://doi.org/10.1161/CIR.0000000000000029)

  3. Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP, Fleisher LA, Jneid H, Mack MJ, McLeod CJ & O’Gara PT. 2017 AHA/ACC focused update of the 2014 AHA/ACC guideline for the management of patients with valvular heart disease. Circulation 2017135 e1159–e1195. https://doi.org/10.1161/CIR.0000000000000503)

    Article  Google Scholar 

  4. Chambers JB. Avoiding needless deaths in aortic stenosis. British Journal of Cardiology 201926 [epub]. https://doi.org/10.5837/bjc.2019.015)

  5. Pellika PA, Nishimura RA, Bailey KR & Tajik AJ. The natural history of adults with asymptomatic, hemodynamically significant aortic stenosis. Journal of the American College of Cardiology 199015. https://doi.org/10.1016/0735-1097(90)90234-G)

  6. Kelly TA, Rothbart RM, Cooper CM, Kaiser D, Sonneker ML & Gibson RS. Comparison of outcome of asymptomatic to symptomatic patients older than 20 years of age with valvular aortic stenosis. American Journal of Cardiology 198816. https://doi.org/10.1016/0002-9149(88)91317-3)

  7. Pierard S, de Meester C, Seldrum S, Pasquet A, Gerber B, Vancraeynest D, Robert A, El Khoury G, Noirhomme P & Vanoverschelde JL. Impact of preoperative symptoms on postoperative survival in severe aortic stenosis: implications for the timing of surgery. Annals of Thoracic Surgery 201497. https://doi.org/10.1016/j.athoracsur.2013.08.059)

  8. Zilbersac R, Lancellotti P, Gilon D, Gabriel H, Schemper M, Maurer G, Massetti M & Rosenhek R. Role of a heart valve clinic programme in the management of patients with aortic stenosis. European Heart Journal Cardiovascular Imaging 201718. https://doi.org/10.1093/ehjci/jew133)

  9. Otto CM, Burwash IG, Legget ME, Munt BI, Fujioka M, Healy NL, Kraft CD, Miyake-Hull CY & Schwaegler RG. Prospective study of asymptomatic valvular aortic stenosis. Clinical, echocardiographic, and exercise predictors of outcome. Circulation 199795. https://doi.org/10.1161/01.CIR.95.9.2262)

  10. Korteland NM, Bras FJ, van Hout FMA, Kluin J, Klautz RJM, Bogers AJJC & Takkenberg JJM. Prosthetic aortic valve selection: current patient experience, preference and knowledge. Open Heart 20152 e000237. https://doi.org/10.1136/openhrt-2015-000237)

    Article  Google Scholar 

  11. Rimington HM, Weinman J & Chambers JB. Predicting outcome after valve replacement. Heart 201096. https://doi.org/10.1136/hrt.2008.160010)

  12. Gardezi SKM, Myerson SG, Chambers J, Coffey S, d’Arcy J, Hobbs FDR, Holt J, Kennedy A, Loudon M, Prendergast A, et al. Cardiac auscultation poorly predicts the presence of valvular heart disease in asymptomatic primary care patients. Heart 2018104. https://doi.org/10.1136/heartjnl-2018-313082)

  13. Draper J, Subbiah S, Bailey R & Chambers JB. Murmur clinic: validation of a new model for detecting heart valve disease. Heart 2019105. https://doi.org/10.1136/heartjnl-2018-313393)

  14. Das P, Pocock C & Chambers J. The patient with a systolic murmur: severe aortic stenosis may be missed during cardiovascular examination. QJM 200093. https://doi.org/10.1093/qjmed/93.10.685)

  15. Chambers JB, Kabir S & Cajeat E. Detection of heart disease by open access echocardiography: a retrospective analysis. British Journal of General Practice 201464. (doi:10.3399/bjgp14X677167)

  16. Leatham A. Auscultation of the Heart and Phonocardiography, 2nd ed. Edinburgh, London and New York: Churchill Livingstone, 1975.

    Google Scholar 

  17. Gaede L, Di Bartolomeo R, van der Kley F, Elsässer A, Iung B & Möllmann H. Aortic valve stenosis: what do people know? A heart valve awareness survey of over 8,800 people aged 60 or over. EuroIntervention 201612. https://doi.org/10.4244/EIJY16M06_02)

  18. Lombard JT & Seltzer A. Valvular aortic stenosis. A clinical and haemodynamic profile of patients. Annals of Internal Medicine 1987106. https://doi.org/10.7326/0003-4819-106-2-292)

  19. Mautner GC, Mautner SL, Cannon RO, Hunsberger SA & Roberts WC. Clinical factors used in predicting aortic valve structure in patients >40 years of age with isolated valvular aortic stenosis. American Journal of Cardiology 199372. https://doi.org/10.1016/0002-9149(93)90159-A)

  20. Aaranow WS & Kronzon I. Prevalence and severity of valvular aortic stenosis determined by Doppler echocardiography and its association with echocardiographic and electrocardiographic left ventricular hypertrophy and physical signs of aortic stenosis in elderly patients. American Journal of Cardiology 199167. https://doi.org/10.1016/0002-9149(91)90542-S)

  21. Saeed S, Rajani R, Parkin D & Chambers JB. Exercise testing in patients with asymptomatic moderate or severe aortic stenosis. Heart 2018104. https://doi.org/10.1136/heartjnl-2018-312939)

  22. Das P, Rimington H & Chambers J. Exercise testing to stratify risk in aortic stenosis. European Heart Journal 200526. https://doi.org/10.1093/eurheartj/ehi250)

  23. Rajani R, Rimington H & Chambers JB. Treadmill exercise in apparently asymptrsma E omatic patients with moderate or severe aortic stenosis: relationship between cardiac index and revealed symptoms. Heart 201096. https://doi.org/10.1136/hrt.2009.181644)

  24. Chambers JB, Rajani R, Parkin D & Saeed S. Rapid early rise in heart rate on treadmill exercise in patients with asymptomatic moderate or severe aortic stenosis: a new prognostic marker? Open Heart 20196 e000950. https://doi.org/10.1136/openhrt-2018-000950)

    Article  Google Scholar 

  25. Lumley MFM. The dynamic interaction of coronary circulation, left ventricle and aortic valve during exercise. PhD Thesis. Supervisors Perera SD, Chambers JB. King's College London, 2016.

    Google Scholar 

  26. Lumley M, Williams R, Asrress KN, Arri S, Briceno N, Ellis H, Rajani R, Siebes M, Piek JJ, Clapp B, et al. Coronary physiology during exercise and vasodilatation in the healthy heart and severe aortic stenosis. Journal of the American College of Cardiology 201668. https://doi.org/10.1016/j.jacc.2016.05.071)

  27. Iung B, Baron G, Butchart EG, Delahaye F, Gohlke-Bärwolf C, Levang OW, Tornos P, Vanaoverschelde J-L, Vermeer F, Boersma E, et al. A prospective survey of patients with valvular heart disease in Europe: the Euro Heart Survey on valvular heart disease. European Heart Journal 200324. https://doi.org/10.1016/s0195-668x(03)00201-x)

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This review did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.

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Correspondence to John B Chambers MD FESC FACC.

Additional information

This paper is part of a series on specialist valve clinics. The Guest Editors for this series were Richard P Steeds and John B Chambers. J B Chambers was not involved in the editorial or review process for this paper, on which he is listed as an author

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Chambers, J.B. How to run a specialist valve clinic: the history, examination and exercise test. Echo Res Pract 6, T23–T28 (2019). https://doi.org/10.1530/ERP-19-0003

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