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Left ventricular speckle tracking echocardiographic evaluation before and after TAVI

Echo Research & Practice volume 7, pages 29–38 (2020)Cite this article

Abstract

Aims: To assess left ventricular (LV) function before and after transcatheter aortic valve implantation (TAVI) using conventional echocardiographic parameters and global longitudinal LV strain (GLS) and compare outcomes between Edwards S3 and Evolut R valves.

Methods and results: Data were collected for consecutive patients undergoing TAVI at Hammersmith hospital between 2015 and 2018. Of the 303 patients, those with coronary artery disease and atrial fibrillation were excluded leading to a total of 85 patients, which constituted our study group. The mean follow-up was 49 ± 39 days. In total, 60% of patients were treated with Edwards S3 and 40% Evolut R. TAVI resulted in an early improvement of GLS (−13.96 to −15.25%, P = 0.01) but not ejection fraction (EF) (47.6 to 50.1%, P = 0.09). LV mass also improved, especially in patients with marked baseline LV hypertrophy (P < 0.001). There were no appreciable differences of LV function improvement and overall LV remodelling after TAVI between the two types of valves used (P = 0.14).

Conclusions: TAVI results in reverse remodelling and improvement of GLS, especially in patients with impaired baseline LV function. There were no differences in the extent of LV function improvement between Edwards S3 and Evolut R valves but there was a greater incidence of aortic regurgitation with Evolut R.

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This review did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.

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Authors and Affiliations

  1. Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK

    Vasiliki Tsampasian MSc MRCP, Vasileios Panoulas PhD FESC, Richard J. Jabbour MBBS MRCP, Neil Ruparelia DPhil MRCP FESC, Iqbal S. Malik PhD FRCP, Nearchos Hadjiloizou MBBS PhD, Angela Frame MSc, Sayan Sen MBBS PhD, Nilesh Sutaria MBChB MD, Ghada W. Mikhail PhD FRCP FESC & Petros Nihoyannopoulos PhD FRCP FESC FACC

  2. Imperial College London, National Heart and Lung Institute, London, UK

    Vasileios Panoulas PhD FESC, Richard J. Jabbour MBBS MRCP, Ghada W. Mikhail PhD FRCP FESC & Petros Nihoyannopoulos PhD FRCP FESC FACC

  3. Harefield Hospital, Royal Brompton and Harefield NHS Foundation Trust, London, UK

    Vasileios Panoulas PhD FESC

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  1. Vasiliki Tsampasian MSc MRCP
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  2. Vasileios Panoulas PhD FESC
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Correspondence to Vasiliki Tsampasian MSc MRCP.

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Tsampasian, V., Panoulas, V., Jabbour, R.J. et al. Left ventricular speckle tracking echocardiographic evaluation before and after TAVI. Echo Res Pract 7, 29–38 (2020). https://doi.org/10.1530/ERP-20-0009

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Echo Research & Practice

ISSN: 2055-0464

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